{"id":8797,"date":"2023-01-29T15:37:21","date_gmt":"2023-01-29T14:37:21","guid":{"rendered":"http:\/\/costops.com\/index.php\/2023\/01\/29\/the-human-genome-needs-updating-but-how-do-we-make-it-fair\/"},"modified":"2023-01-29T15:37:21","modified_gmt":"2023-01-29T14:37:21","slug":"the-human-genome-needs-updating-but-how-do-we-make-it-fair","status":"publish","type":"post","link":"http:\/\/costops.com\/index.php\/2023\/01\/29\/the-human-genome-needs-updating-but-how-do-we-make-it-fair\/","title":{"rendered":"The human genome needs updating. But how do we make it fair?"},"content":{"rendered":"<p>Healthcare\u2019s standard genome is mostly based on one American. As we enter the era of personalised medicine, this bias has drawbacks for much of the world\u2019s population<\/p>\n<p>In June 2000, <a href=\"https:\/\/www.youtube.com\/watch?v=slRyGLmt3qc\">Bill Clinton, the then US president, stood smilingly <\/a>next to the leaders of the <a href=\"https:\/\/www.theguardian.com\/science\/human-genome-project\">Human Genome Project. <\/a>\u201cIn genetic terms, all human beings, regardless of race, are more than 99.9% the same,\u201d he declared. That was the message when the <a href=\"https:\/\/www.genome.gov\/10001356\/june-2000-white-house-event\">first draft of the human genome sequence was revealed<\/a> at the White House.<\/p>\n<p>The single string of As, Ts, Cs and Gs eventually became the first human reference genome. Since <a href=\"https:\/\/www.theguardian.com\/science\/2003\/apr\/14\/genetics.research\">its publication in 2003<\/a>, the reference has revolutionised genome sequencing and helped scientists find thousands of disease-causing mutations. Yet at its core is a somewhat ironic problem: the code meant to represent the human species is <a href=\"https:\/\/www.nytimes.com\/2013\/04\/16\/science\/the-human-genome-project-then-and-now.html\">mostly based on just one man<\/a> from Buffalo, New York.<\/p>\n<p> <a href=\"https:\/\/www.theguardian.com\/science\/2023\/jan\/29\/the-human-genome-needs-updating-but-how-do-we-make-it-fair\">Continue reading&#8230;<\/a><br \/>\n<img src=\"https:\/\/i.guim.co.uk\/img\/media\/fdde4086b6dec122833b6f07b3e7e5a131cd5363\/0_2_4125_2475\/master\/4125.jpg?width=140&amp;quality=85&amp;auto=format&amp;fit=max&amp;s=16b5c98882f3a9e56c67eb56c3ea567a\" title=\"The human genome needs updating. But how do we make it fair?\" \/>Healthcare\u2019s standard genome is mostly based on one American. As we enter the era of personalised medicine, this bias has drawbacks for much of the world\u2019s population<br \/>\nIn June 2000, Bill Clinton, the then US president, stood smilingly next to the leaders of the Human Genome Project. \u201cIn genetic terms, all human beings, regardless of race, are more than 99.9% the same,\u201d he declared. That was the message when the first draft of the human genome sequence was revealed at the White House.<br \/>\nThe single string of As, Ts, Cs and Gs eventually became the first human reference genome. Since its publication in 2003, the reference has revolutionised genome sequencing and helped scientists find thousands of disease-causing mutations. Yet at its core is a somewhat ironic problem: the code meant to represent the human species is mostly based on just one man from Buffalo, New York. Continue reading&#8230;Technology | The Guardian<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Healthcare\u2019s standard genome is mostly based on one American. As we enter the era of personalised medicine, this bias has drawbacks for much of the world\u2019s population In June 2000, Bill Clinton, the then US president, stood smilingly next to the leaders of the Human Genome Project. \u201cIn genetic terms, all human beings, regardless of &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"\" href=\"http:\/\/costops.com\/index.php\/2023\/01\/29\/the-human-genome-needs-updating-but-how-do-we-make-it-fair\/\"> <span class=\"screen-reader-text\">The human genome needs updating. But how do we make it fair?<\/span> Read More &raquo;<\/a><\/p>\n","protected":false},"author":0,"featured_media":8798,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/posts\/8797"}],"collection":[{"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/comments?post=8797"}],"version-history":[{"count":0,"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/posts\/8797\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/media\/8798"}],"wp:attachment":[{"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/media?parent=8797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/categories?post=8797"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/costops.com\/index.php\/wp-json\/wp\/v2\/tags?post=8797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}